Hydrochloric Acid → HCID 66593842, compound

Participants

Reaction Conditions

Reaction Steps

Compound 19-3 (930 mg) was dissolved in ethanol (20 ml), concentrated hydrochloric acid (2 ml) was added, and the mixture was stirred at 80° C. for 1.5 hr. The reaction mixture was concentrated, and the residue was washed with diethyl ether to give a white powder. The white powder was purified by HPLC, and the obtained residue was converted to hydrochloride by adding hydrogen chloride containing ether (1 mol/l, 15 ml). The precipitate was collected by filtration and dried to give the object product (460 mg) as a white powder.

Provenance & Evidence