3-(3,4-Dichlorophenyl)prop-2-yn-1-ol → 3-(3,4-Dichlorophenyl)propan-1-ol

Participants

Reaction Conditions

Reaction Steps

A suspension of Compound 38-1 (3.21 g) and chlorotris(triphenylphosphine)rhodium(I) (1.60 g) in toluene (100 ml) was stirred under a hydrogen atmosphere at 60° C. for 10 hr. The reaction mixture was filtered through celite and concentrated. The obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=98:2-80:20) to give the object product (2.83 g) as a brown oil.

Provenance & Evidence