Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59407611 | HCID 59407611 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66593759 | HCID 66593759 | — |
Reaction Steps
Compound 45-5 (640 mg) was dissolved in ethanol (15 ml), concentrated hydrochloric acid (1.5 ml) was added, and the mixture was stirred at 80° C. for 2 hr. The reaction mixture was concentrated, and the residue was washed with diethyl ether to give the object product (480 mg) as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08129361B2 |
|---|
| Source dataset | uspto-grants-2012_03 |
|---|
| ORD ID | ord-b5912ea3b27a4572a60d346c2709ef2d |
|---|
| Source note | uspto-grants-2012_03 |
|---|
