反应详情

温度

60 °C

A suspension of Compound 54-1 (2.58 g) and chlorotris(triphenylphosphine)rhodium(I) (1.50 g) in toluene (80 ml) was stirred under a hydrogen atmosphere at 60° C. for 11 hr. The reaction mixture was filtered through celite and concentrated. The obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=99:1-80:20) to give the object product (2.11 g) as a brown oil.

1. filtrationThe reaction mixture was filtered through celite
2. concentrationconcentrated
3. customThe obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate=99:1-80:20)