Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59407873 | HCID 59407873 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86761522 | HCID 86761522 | 163% |
Reaction Steps
Compound 66-4 (740 mg) was dissolved in ethanol (15 ml), concentrated hydrochloric acid (1.5 ml) was added, and the mixture was stirred at 80° C. for 2 hr. The reaction mixture was concentrated, and the residue was washed with diethyl ether to give the object product (500 mg) as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08129361B2 |
|---|
| Source dataset | uspto-grants-2012_03 |
|---|
| ORD ID | ord-13a514e5b6254fdfac03f3a0b88a6923 |
|---|
| Source note | uspto-grants-2012_03 |
|---|
