Dimethyl Sulfoxide → 5-Chloro-N-((1-(2-(3-oxopiperazin-1-yl)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

HRID 109379Notes

Reaction equation

HRID 109379 reaction equation
[CH3:37][S:38]([CH3:39])=[O:40].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[c:17]([F:29])[cH:18][c:19](-[n:22]4[c:23](=[O:28])[cH:24][cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1.[O:30]=[C:31]1[NH:32][CH2:33][CH2:34][NH:35][CH2:36]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][CH2:10][c:11]2[n:12][cH:13][n:14](-[c:16]3[c:17]([N:35]4[CH2:34][CH2:33][NH:32][C:31](=[O:30])[CH2:36]4)[cH:18][c:19](-[n:22]4[c:23](=[O:28])[cH:24][cH:25][cH:26][cH:27]4)[cH:20][cH:21]3)[cH:15]2)[s:6]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 231360Piperazin-2-oneHCID 24760453HCID 24760453, compound

Product 1

HCID 247605285-Chloro-N-((1-(2-(3-oxopiperazin-1-yl)-4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-imidazol-4-yl)methyl)thiophene-2-carboxamide

Sources & evidence

ORD record
ord-fd3d718d76884de4a3166a20208e82ed
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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