HCID 59864416, compound → HCID 69310161, compound

Participants

Reaction Steps

30 g (74.9 mmol) of 1-tert-butyldimethylsilyloxy-3-pentyl-7,8,9,10-tetrahydro-benzo[c]-chromen-6-one were hydrogenated to completion on palladium/carbon in THF. The catalyst was filtered off, the solvent was removed in vacuo, and the residue was filtered through silica gel with heptane/ethyl acetate (15:1), giving 24.5 g (81%) of (6aR*,10aS*)-1-tert-butyldimethylsilyloxy-3-pentyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-6-one as a colourless oil.

Provenance & Evidence