HuagongsheHuagongshe Chemistry Print Report · For research reference only
{4-[2-(Pyrrolidin-1-yl)ethyl]-1H-pyrrol-2-yl}methanol → 4-[2-(Pyrrolidin-1-yl)ethyl]-1H-pyrrole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {4-[2-(Pyrrolidin-1-yl)ethyl]-1H-pyrrol-2-yl}methanol | HCID 66636497 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-[2-(Pyrrolidin-1-yl)ethyl]-1H-pyrrole-2-carbaldehyde | HCID 86650825 | — |
Reaction Steps
To a solution of the product obtained in Step I (0.09 g) in THF (3.8 ml) there is added activated MnO2 (0.315 g). After stirring for 20 hours at ambient temperature, the mixture is filtered and the filtrate is evaporated to dryness to yield the title product, which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133889B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-0e7dae2a37bb4753ae5895f28825af2f |
| Source note | uspto-grants-2012_03 |