1-[4-(Bromomethyl)Phenyl]-1H-Pyrazole → HCID 25115065, compound

HRID 1094057Notes

Reaction equation

HRID 1094057 reaction equation
[NH2:1][C:2]1[C:3]([C:25]#[N:26])=[C:4]([C:16]2[CH:21]=[C:20]([F:22])[CH:19]=[CH:18][C:17]=2[O:23][CH3:24])[C:5]2[C:10](=[O:11])[N:9]([CH3:12])[C:8](=[O:13])[N:7]([CH3:14])[C:6]=2[N:15]=1.Br[CH2:28][C:29]1[CH:34]=[CH:33][C:32]([N:35]2[CH:39]=[CH:38][CH:37]=[N:36]2)=[CH:31][CH:30]=1>>[N:35]1([C:32]2[CH:33]=[CH:34][C:29]([CH2:28][NH:1][C:2]3[C:3]([CH2:25][NH2:26])=[C:4]([C:16]4[CH:21]=[C:20]([F:22])[CH:19]=[CH:18][C:17]=4[O:23][CH3:24])[C:5]4[C:10](=[O:11])[N:9]([CH3:12])[C:8](=[O:13])[N:7]([CH3:14])[C:6]=4[N:15]=3)=[CH:30][CH:31]=2)[CH:39]=[CH:38][CH:37]=[N:36]1

Participants

3

Reactant 2

HCID 27764791-[4-(Bromomethyl)Phenyl]-1H-PyrazoleHCID 59353132HCID 59353132, compound

Product 1

HCID 25115065HCID 25115065, compound

Procedure

The synthesis of title compounds started from Compound 70a and 1-(4-(bromomethyl)phenyl)-1H-pyrazole, according to procedures described in the synthesis of Compound 56. MS [m+H] calc'd C27H27FN7O3 516; found 516.

Workup

  1. customThe synthesis of title compounds

Sources & evidence

ORD record
ord-44b51d76db7b4382a8d9d6a9c33d3d72
Source dataset
uspto-grants-2012_03
Patent number
US08133898B2

Reaction notes

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