HCID 24970297, compound → HCID 25115529, compound

Participants

Reaction Steps

The synthesis of title compounds started from Compound 70a and 1-(bromomethyl)-3-isobutoxybenzene, according to procedures described in the synthesis of Compound 70. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 0.96 (d, J=6.6 Hz, 6H) 1.95-2.04 (m, 1H) 3.19 (s, 3H) 3.53 (s, 1H) 3.65 (d, J=8.6 Hz, 2H) 3.69 (s, 3H) 3.88 (d, J=14.4 Hz, 1H) 4.55 (d, J=14.9 Hz, 1H) 4.68 (d, J=14.9 Hz, 1H) 6.67 (dd, J=8.3, 3.0 Hz, 1H) 6.73 (dd, J=7.9, 2.1 Hz, 1H) 6.85-6.92 (m, 2H) 6.98 (dd, J=9.1, 4.3 Hz 1H) 7.05-7.12 (m, 1H) 7.14 (t, J=8.0 Hz 1H). MS [m+H] calc'd C28H33FN5O4 522. found 522.

Provenance & Evidence