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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094263Generated: October 31, 2026

2'-Fluorobiphenyl-2-carboxylic acid → (R)-[3-(5-Bromo-pyrimidin-2-ylamino)-piperidin-1-yl]-(2'-fluoro-biphenyl-2-yl)-methanone

https://huagongshe.com/reaction/1094263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2'-Fluorobiphenyl-2-carboxylic acidHCID 5109229—
ReactantHCID 66639492HCID 66639492—
Product(R)-[3-(5-Bromo-pyrimidin-2-ylamino)-piperidin-1-yl]-(2'-fluoro-biphenyl-2-yl)-methanoneHCID 24968731—

Reaction Steps

prepared by reaction of 2′-fluoro-biphenyl-2-carboxylic acid with (R)-(5-bromo-pyrimidin-2-yl)-piperidine-3-yl-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133901B2
Source datasetuspto-grants-2012_03
ORD IDord-33fd4d89f5d74c5d83e89f9f02408cd4
Source noteuspto-grants-2012_03