5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → HCID 66639692, compound

HRID 1094266Notes

Reaction equation

HRID 1094266 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[S:12][C:11]([CH3:13])=[N:10][C:9]=2[C:14]([OH:16])=O)=[CH:4][CH:3]=1.[NH:17]1[CH2:22][CH2:21][CH2:20][CH:19]([NH:23][C:24]([C:26]2[CH:27]=[CH:28][CH:29]=[C:30]3[O:34][CH:33]=[CH:32][C:31]=23)=[O:25])[CH2:18]1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[S:12][C:11]([CH3:13])=[N:10][C:9]=2[C:14]([N:17]2[CH2:22][CH2:21][CH2:20][CH:19]([NH:23][C:24]([C:26]3[CH:27]=[CH:28][CH:29]=[C:30]4[O:34][CH:33]=[CH:32][C:31]=34)=[O:25])[CH2:18]2)=[O:16])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 223241255-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 66639463HCID 66639463, compound

Product 1

HCID 66639692HCID 66639692, compound

Procedure

prepared by reaction of 5-(4-fluoro-phenyl)-2-methyl-thiazole-4-carboxylic acid with (RS)-benzofuran-4-carboxylic acid piperidin-3-ylamide.

Sources & evidence

ORD record
ord-6e5edca2ab0b4ebc8dd4684acf1c4c8c
Source dataset
uspto-grants-2012_03
Patent number
US08133901B2

Reaction notes

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