2-(3-chlorophenyl)benzoic Acid → 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(r)-1-(3'-chloro-biphenyl-2-carbonyl)-piperidin-3-yl]-amide

HRID 1094281Notes

Reaction equation

HRID 1094281 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][C@@H:3]([NH:7][C:8]([C:10]2[N:17]3[C:13]([S:14][CH:15]=[CH:16]3)=[N:12][C:11]=2[CH3:18])=[O:9])[CH2:2]1.[Cl:19][C:20]1[CH:21]=[C:22]([C:26]2[C:27]([C:32](O)=[O:33])=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:23]=[CH:24][CH:25]=1>>[Cl:19][C:20]1[CH:21]=[C:22]([C:26]2[C:27]([C:32]([N:1]3[CH2:6][CH2:5][CH2:4][C@@H:3]([NH:7][C:8]([C:10]4[N:17]5[C:13]([S:14][CH:15]=[CH:16]5)=[N:12][C:11]=4[CH3:18])=[O:9])[CH2:2]3)=[O:33])=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:23]=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 27574152-(3-chlorophenyl)benzoic AcidHCID 66639497(r)-6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid piperidin-3-ylamide

Product 1

HCID 666394336-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(r)-1-(3'-chloro-biphenyl-2-carbonyl)-piperidin-3-yl]-amide

Procedure

prepared by reaction of (R)-6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid piperidin-3-ylamide with 3′-chloro-biphenyl-2-carboxylic acid.

Sources & evidence

ORD record
ord-205912e92e514e819867c9b6877352a8
Source dataset
uspto-grants-2012_03
Patent number
US08133901B2

Reaction notes

Loading…