HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiophenecarboxylic acid → 5-Propylthiophene-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiophenecarboxylic acid | HCID 10700 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | 5-Ethylthiophene-2-carboxylic acid | HCID 588192 | — |
| Product | 5-Propylthiophene-2-carboxylic acid | HCID 3164314 | — |
Reaction Steps
The title compound is prepared in analogy to 5-ethyl-thiophene-2-carboxylic acid starting from 2-thiophenecarboxylic acid and 1-iodopropane; LC-MS: tR=0.87 min, 1H NMR (CDCl3): δ 0.99 (t, J=7.0 Hz, 3H), 1.74 (hex, J=7.3 Hz, 2H), 2.83 (t, J=7.6 Hz, 2H), 6.82 (d, J=3.5 Hz, 1H), 7.73 (d, J=3.8 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133910B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-e4e5214f5429489399cb1863ff9dfa15 |
| Source note | uspto-grants-2012_03 |