Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094289Generated: October 25, 2026

2-Thiophenecarboxylic acid → 5-Butylthiophene-2-carboxylic acid

https://huagongshe.com/reaction/1094289

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenecarboxylic acidHCID 10700—
ReactantButyl iodideHCID 10962—
Reactant5-Ethylthiophene-2-carboxylic acidHCID 588192—
Product5-Butylthiophene-2-carboxylic acidHCID 12326223—

Reaction Steps

The title compound is prepared in analogy to 5-ethyl-thiophene-2-carboxylic acid starting from 2-thiophenecarboxylic acid and 1-iodobutane; LC-MS: tR=0.92 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133910B2
Source datasetuspto-grants-2012_03
ORD IDord-e8c4346ec62a4c0e9a26c9fe6585a306
Source noteuspto-grants-2012_03