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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094313Generated: October 29, 2026

4-Benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazide → 2-Ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenol

https://huagongshe.com/reaction/1094313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazideHCID 59202026—
Reactant4-Methyl-5-(2-methyl-propenyl)-thiophene-2-carboxylic acidHCID 59202027—
Product2-Ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenolHCID 136029943—

Reaction Steps

2-Ethyl-4-[5-(5-isobutyl-4-methyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenol is prepared from 4-methyl-5-(2-methyl-propenyl)-thiophene-2-carboxylic acid and 4-benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazide in analogy to Example 29; LC-MS: tR=1.13 min, [M+1]+=357.49.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133910B2
Source datasetuspto-grants-2012_03
ORD IDord-a75976e3675e48e89d2b88c902811dd8
Source noteuspto-grants-2012_03