4-Iodo-1,2-dimethylbenzene → (3,4-Dimethyl-phenyl)-(2-pyridin-3-yl-ethyl)-amine

HRID 1094363Notes

Reaction equation

HRID 1094363 reaction equation
I[C:2]1[CH:3]=[C:4]([CH3:9])[C:5]([CH3:8])=[CH:6][CH:7]=1.[N:10]1[CH:15]=[CH:14][CH:13]=[C:12]([CH2:16][CH2:17][NH2:18])[CH:11]=1>>[CH3:9][C:4]1[CH:3]=[C:2]([NH:18][CH2:17][CH2:16][C:12]2[CH:11]=[N:10][CH:15]=[CH:14][CH:13]=2)[CH:7]=[CH:6][C:5]=1[CH3:8]

Participants

3

Reactant 2

HCID 1416464-Iodo-1,2-dimethylbenzeneHCID 8540512-(Pyridin-3-yl)ethan-1-amine

Product 1

HCID 55169203(3,4-Dimethyl-phenyl)-(2-pyridin-3-yl-ethyl)-amine

Procedure

In analogy to the procedure described for the synthesis of example 22, step 1, the title compound was prepared from 4-iodo-o-xylene and 2-pyridin-3-yl-ethylamine (CAS: 20173-24-4). MS (m/e): 227.2 [M+H]+.

Workup

  1. customIn analogy to the procedure described for the synthesis of example 22, step 1

Sources & evidence

ORD record
ord-3dba1fdaf6fb43f9ad1e90c0827fb9c5
Source dataset
uspto-grants-2012_03
Patent number
US08133909B2

Reaction notes

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