p-Methylphenethylamine → HCID 58007510, compound

HRID 1094381Notes

Reaction equation

Br[C:2]1[S:6][C:5]([CH3:7])=[N:4][C:3]=1[CH3:8].[C:9]1([CH3:18])[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][NH2:17])=[CH:11][CH:10]=1>>[CH3:7][C:5]1[S:6][C:2]([NH:17][CH2:16][CH2:15][C:12]2[CH:13]=[CH:14][C:9]([CH3:18])=[CH:10][CH:11]=2)=[C:3]([CH3:8])[N:4]=1

Participants

Reactant 2

HCID 76751p-Methylphenethylamine

HCID 2986285-Bromo-2,4-dimethyl-1,3-thiazole

Product 1

HCID 58007510HCID 58007510, compound

Procedure

In analogy to the procedure described for the synthesis example 32 (step 1), the title compound (2,4-dimethyl-thiazol-5-yl)-(2-p-tolyl-ethyl)-amine (MS m/e: 247.0 [M+H]+) was prepared from 5-bromo-2,4-dimethyl-1,3thiazole and 2-(p-tolyl)ethylamine.

Workup

customIn analogy to the procedure described for the synthesis example 32 (step 1)

Sources & evidence

ORD record: ord-6cceefc68f2546c092c30c932244d6c5
Source dataset: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08133909B2

Reaction notes

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