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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094388Generated: November 1, 2026

1-(2-Bromoethyl)-4-(trifluoromethyl)benzene → N-(6-chloro-pyridin-3-yl)-2-oxo-2-phenyl-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-acetamide

https://huagongshe.com/reaction/1094388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Bromoethyl)-4-(trifluoromethyl)benzeneHCID 14949941—
ReactantHCID 58007569HCID 58007569—
ProductN-(6-chloro-pyridin-3-yl)-2-oxo-2-phenyl-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-acetamideHCID 58007544—

Reaction Steps

In analogy to the procedure described for the synthesis example 43 (step 2), the title compound N-(6-chloro-pyridin-3-yl)-2-oxo-2-phenyl-N-[2-(4-trifluoromethyl-phenyl)-ethyl]-acetamide (MS m/e: 433.2 [M+H]+) was prepared from N-(6-chloro-pyridin-3-yl)-2-oxo-2-phenyl-acetamide and 1-(2-bromo-ethyl)-4-trifluoromethyl-benzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-36f48ec2eee5470f920e852f91cdea7b
Source noteuspto-grants-2012_03