反应详情

In analogy to example 55, 6-Amino-chroman-4-ol (as described in WO 2005037830), (6-Trifluoromethyl-pyridin-3-yl)-acetonitrile & (S)-(+)-O-acetyl-L-mandelic acid were successively coupled then hydrolysed to give the target compound. MS(m/e): 473.1 [M+H]+.

1. customhydrolysed to give the target compound