HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dimethylaniline → HCID 44546501, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dimethylaniline | HCID 7248 | — |
| Reactant | 2-Ethenyl-5-fluoropyridine | HCID 66637427 | — |
| Reactant | acetyl (2S)-2-hydroxy-2-phenylacetate | HCID 87431886 | — |
| Product | HCID 44546501 | HCID 44546501 | — |
Reaction Steps
In analogy to example 25 step 1 and 26 step 1-2, (3,4-dimethyl-phenyl)-[2-(5-fluoro-pyridin-2-yl)-ethyl]-amine obtained by reacting 5-Fluoro-2-vinyl-pyridine (CAS: 869108-71-4) with 3,4-dimethylaniline was coupled with (S)-(+)-O-acetyl-L-mandelic acid then hydrolysed to provide the title compound. MS(m/e): 379.3 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-8cfe554ec98e41caa73095a30adb62d3 |
| Source note | uspto-grants-2012_03 |