(5-Bromo-2-fluorophenyl)methanol → {2-Fluoro-5-[2-(5-trifluoromethyl-pyridin-2-yl)-ethylamino]-phenyl}-methanol

Participants

Reaction Steps

In analogy to the procedure described for the synthesis example 71 (step 1), the title compound {2-fluoro-5-[2-(5-trifluoromethyl-pyridin-2-yl)-ethylamino]-phenyl}-methanol (MS m/e: 315.1 [M+H]+) was prepared from (5-bromo-2-fluoro-phenyl)-methanol instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.

Provenance & Evidence