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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094431Generated: November 1, 2026

4-Bromo-1-methoxy-2-methylbenzene → HCID 58007575, compound

https://huagongshe.com/reaction/1094431

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-1-methoxy-2-methylbenzeneHCID 608315—
Reactant2-(5-Trifluoromethyl-pyridin-2-YL)-ethylamineHCID 18071344—
ProductHCID 58007575HCID 58007575—

Reaction Steps

In analogy to the procedure described for the synthesis example 71 (step 1), the title compound (4-methoxy-3-methyl-phenyl)-[2-(5-trifluoromethyl-pyridin-2-yl)-ethyl]-amine (MS m/e: 311.3 [M+H]+) was prepared from 4-bromo-2-methyl-anisole instead of 6-bromo-2,3-dihydro-benzofuran and 2-(5-trifluoromethyl-pyridin-2-yl)-ethylamine instead of 2-(6-trifluoromethyl-pyridin-3-yl)-ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-fea8ba4acbc54bfaa8ad4638f5a1e24b
Source noteuspto-grants-2012_03