HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Aminoquinoline → HCID 58007579, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Aminoquinoline | HCID 11373 | — |
| Reactant | 4-(Trifluoromethyl)phenylacetonitrile | HCID 75359 | — |
| Reactant | acetyl (2S)-2-hydroxy-2-phenylacetate | HCID 87431886 | — |
| Product | HCID 58007579 | HCID 58007579 | — |
Reaction Steps
In analogy to example 104 quinolin-6-ylamine, 4-(trifluoromethyl)phenylacetonitrile & (+)-O-Acetyl-L-Mandelic Acid were successively coupled then hydrolysed to give after silica gel chromatography the target compound. MS(m/e): 451.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133909B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-2518aa5431a84838acd37ed5a5dc62a9 |
| Source note | uspto-grants-2012_03 |