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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094444Generated: October 27, 2026

2-(4-Fluorophenyl)-2-oxoacetic Acid → HCID 178434302, compound

https://huagongshe.com/reaction/1094444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)-2-oxoacetic AcidHCID 579440—
Reactant3-Pyridineacetonitrile, 6-(trifluoromethyl)-HCID 50851127—
ReactantHCID 178434299HCID 178434299—
ProductHCID 178434302HCID 178434302—

Reaction Steps

In analogy to example 47 (steps 1-3), 3-Methyl-1H-indazol-5-ylamine, (6-Trifluoromethyl-pyridin-3-yl)-acetonitrile & (4-fluoro-phenyl)-oxo-acetic acid were successively coupled to give after silica gel chromatography the target compound. MS(m/e): 471.1 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133909B2
Source datasetuspto-grants-2012_03
ORD IDord-1525502d2bc742a983d588e9efe65693
Source noteuspto-grants-2012_03