HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-2-oxopropionate-1-propyl ester → 2-Methyl-8-fluoro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid n-propyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-2-oxopropionate-1-propyl ester | HCID 11513992 | — |
| Reactant | 6-Fluoro-alpha-methyltryptamine | HCID 15289992 | — |
| Product | 2-Methyl-8-fluoro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid n-propyl ester | HCID 66640112 | — |
Reaction Steps
2-Methyl-8-fluoro-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid n-propyl ester was prepared in a manner similar to that described in Example 1A by using α-methyl-6-fluorotryptamine and n-propyl 3-bromopyruvate; MS (ESI): 303 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08133992B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-0e5b6fc892a2497297206f4ee806e22c |
| Source note | uspto-grants-2012_03 |