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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1094559Generated: October 26, 2026

Alpha-Ethyltryptamine → 2-Ethyl 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid n-propyl ester

https://huagongshe.com/reaction/1094559

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAlpha-EthyltryptamineHCID 8367—
ReactantEthyl bromopyruvateHCID 66144—
Reactant3-Bromo-2-oxopropionate-1-propyl esterHCID 11513992—
Product2-Ethyl 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid n-propyl esterHCID 66639953—

Reaction Steps

2-Ethyl 1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylic acid n-propyl ester was prepared in a manner similar to that described in Example 1A but replacing tryptamine hydrochloride with α-ethyl tryptamine and ethyl 3-bromopyruvate with n-propyl 3-bromopyruvate; MS (ESI): 303 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08133992B2
Source datasetuspto-grants-2012_03
ORD IDord-538360a69c004dcf8b98b0bb27a89bed
Source noteuspto-grants-2012_03