HuagongsheHuagongshe Chemistry Print Report · For research reference only
proline dl-form → Pyrrolidine-2-carboxylic acid [4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | proline dl-form | HCID 614 | — |
| Reactant | 4-Methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylamine | HCID 11557499 | — |
| Product | Pyrrolidine-2-carboxylic acid [4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-yl]-amide | HCID 72435184 | 55% |
Reaction Steps
Pet-160 was prepared according to the general procedure described hereinabove and the procedure described above for the preparation of Pet-154, using pyrrolidine-2-carboxylic acid and 4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylamine (Pet-10) as the starting materials, in an overall yield of 55%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134010B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-d23a41a001c54417acdb378c20bdae60 |
| Source note | uspto-grants-2012_03 |