HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylparaben → HCID 57743438, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylparaben | HCID 7456 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Fluoro-5-iodobenzaldehyde | HCID 16217058 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743438 | HCID 57743438 | 69.1% |
Reaction Steps
In a manner similar to the method described in Example 50a, 2-fluoro-5-iodobenzaldehyde (3.6 g, 14.4 mmol) (Aldrich) was reacted with methyl 4-hydroxybenzoate (2.62 g, 17.3 mmol) and K2CO3 in N,N-dimethylacetamide to give 4-(2-formyl-4-iodo-phenoxy)-benzoic acid methyl ester as a yellow oil (Yield 3.8 g, 69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-a582058af6634970aaecc9f633338009 |
| Source note | uspto-grants-2012_03 |