HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57743385, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(Trifluoromethyl)phenol | HCID 67874 | — |
| Reactant | 5-Chloro-2-fluorobenzaldehyde | HCID 2773586 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743385 | HCID 57743385 | 58.2% |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-chloro-2-fluorobenzaldehyde (0.88 g, 5.6 mmol) (Beta Pharma) was reacted with 4-trifluoromethylphenol (1 g, 6.6 mmol)(Aldrich) and K2CO3 in N,N-dimethylacetamide to give 5-chloro-2-(4-trifluoromethyl-phenoxy)-benzaldehyde as a yellow solid (Yield 0.98 g, 58%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-699a623fb2df4e7d906f41f61dbe6e22 |
| Source note | uspto-grants-2012_03 |