HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 57743260, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | HCID 57743200 | HCID 57743200 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 57743260 | HCID 57743260 | 100% |
Reaction Steps
In a manner similar to the method described in Example 60b, 5-bromo-2-[4-(3-hydroxy-propyl)-phenoxy]-benzaldehyde (9 g, 27 mmol) was reacted with tert-butyldimethylchlorosilane (4.45 g, 30 mmol) and imidazole in N,N-dimethylformamide to give 5-bromo-2-{4-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-phenoxy}-benzaldehyde as a brown oil (Yield 12 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-b1f4564800404d1e8c40bbf72202c342 |
| Source note | uspto-grants-2012_03 |