HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 57743398, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(Methylthio)phenol | HCID 14086 | — |
| Reactant | 5-Chloro-2-fluorobenzaldehyde | HCID 2773586 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743398 | HCID 57743398 | 98.1% |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-chloro-2-fluoro-benzaldehyde (2 g, 12.8 mmol) (Beta Pharma) was reacted with 4-(methylthio)phenol (1.97 g, 14 mmol) (Aldrich) and K2CO3 in N,N-dimethylacetamide to give 5-chloro-2-(4-methylsulfanyl-phenoxy)-benzaldehyde as a brown oil (Yield 3.5 g, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-1b6acd97eec144a7a8dc23ce04f09305 |
| Source note | uspto-grants-2012_03 |