HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenol → HCID 57743313, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenol | HCID 980 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Chloro-2-fluorobenzaldehyde | HCID 2773586 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57743313 | HCID 57743313 | 73.7% |
Reaction Steps
In a manner similar to the method described in Example 50a, 5-chloro-2-fluoro-benzaldehyde (1.71 g, 10.9 mmol) (Beta Pharma) was reacted with 4-nitrophenol (1.67 g, 12 mmol) (Aldrich) and K2CO3 in N,N-dimethylacetamide to give 5-chloro-2-(4-nitro-phenoxy)-benzaldehyde as a brown oil (Yield 2.23 g, 73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-78c75751cb4f4917bf61dbdd918a9029 |
| Source note | uspto-grants-2012_03 |