HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1,4-Dioxaspiro(4.5)decan-8-yl methanesulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 1,4-Dioxaspiro(4.5)decan-8-ol | HCID 567352 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,4-Dioxaspiro(4.5)decan-8-yl methanesulfonate | HCID 14966741 | 90% |
Reaction Steps
In a manner similar to the method described in example 32a, 1,4-dioxa-spiro[4.5]decan-8-ol (5.1 g, 32 mmol) (Alfa) was reacted with methanesulfonyl chloride (3.7 g, 32 mmol, Aldrich) and triethylamine in dichloromethane to give methanesulfonic acid 1,4-dioxa-spiro[4.5]dec-8-yl ester as a light yellow oil (Yield 6.8 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08134001B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-f02a4747637c4c7ea5a5a36cfad9df88 |
| Source note | uspto-grants-2012_03 |