HCID 44258472, compound → HCID 66783912, compound
Reaction equation
[CH2:1]([N:3]([CH2:6][CH2:7]NC1C=CC(C2OC3C(C(=O)C=2)=C(O)C(OC)=C(O)C=3)=CC=1)[CH2:4][CH3:5])[CH3:2].[CH2:30]1[O:42][C:41]2[CH:40]=[C:39]3[C:34]([C:35](=[O:50])[CH:36]=[C:37]([C:43]4[CH:48]=[CH:47][C:46]([OH:49])=[CH:45][CH:44]=4)[O:38]3)=[C:33]([OH:51])[C:32]=2[O:31]1>>[CH2:1]([N:3]([CH2:6][CH2:7][O:49][C:46]1[CH:45]=[CH:44][C:43]([C:37]2[O:38][C:39]3[C:34]([C:35](=[O:50])[CH:36]=2)=[C:33]([OH:51])[C:32]2[O:31][CH2:30][O:42][C:41]=2[CH:40]=3)=[CH:48][CH:47]=1)[CH2:4][CH3:5])[CH3:2]Participants
3
Procedure
Similar to the preparation of 4′-[2-(N,N-diethylamino)ethylamino]-5,7-dihydroxy-6-methoxyflavone (discussed above), the title compound is prepared starting from 6,7-methylenedioxy-5,4′-dihydroxyflavone.
Sources & evidence
- ORD record
- ord-b7e19809809348cc9a88ae06f5118600
- Source dataset
- uspto-grants-2012_03
- Patent number
- US08138165B2
Reaction notes
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