反应详情

A mixture of ethyl 4-(2-nitrophenyl)-3-oxobutanoate (17.04 g, 67.8 mmol), 10% palladium on carbon (3.6 g), and ethanol (280 mL) was placed under hydrogen pressure (50 psi, 3.4×105 Pa) on a Parr apparatus for 96 hours. The reaction mixture was filtered through a layer of CELITE filter aid. The filtrate was concentrated under reduced pressure to provide crude ethyl 1H-indol-2-ylacetate.

1. customfor 96 hours
2. filtrationThe reaction mixture was filtered through a layer of CELITE
3. filtrationfilter aid
4. concentrationThe filtrate was concentrated under reduced pressure