Pyrrolidine → HCID 57475112, compound

Participants

Reaction Conditions

Reaction Steps

Pyrrolidine (1.95 g, 2.29 ml, 27.5 mmol), 1,2,3-triazole (2.07 g, 30 mmol) and molecular sieve 4 Å (7.14 g) were added to a solution of 1,4 dioxaspiro[4,5]decan-8-one (3.9 g, 25 mmol) in toluene (40 ml). The mixture was stirred at 90° C. for 7 h. The solution was then decanted and immediately reacted further.

Provenance & Evidence