7-(Tetrahydro-2h-pyran-4-yloxy)imidazo[1,2-a]pyridine → (trans)-benzyl 3-fluoro-4-(2-(7-(tetrahydro-2H-pyran-4-yloxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-yloxy)piperidine-1-carboxylate

Participants

Reaction Steps

Prepared according to the procedure used for Example 1, Step D, using 7-(tetrahydro-2H-pyran-4-yloxy)imidazo[1,2-a]pyridine in place of 7-(2-methoxyethoxy)imidazo[1,2-a]pyridine and (trans)-benzyl 4-(2-chloroquinolin-8-yloxy)-3-fluoropiperidine-1-carboxylate in place of 2,8-dibromoquinoline. MS APCI (+) m/z 597 (M+1) detected.

Provenance & Evidence