Tert-butyl cis-3-fluoro-4-(methylsulfonyloxy)piperidine-1-carboxylate → 2-(7-Ethylimidazo[1,2-a]pyridin-3-yl)-8-((trans)-3-fluoropiperidin-4-yloxy)quinoline

Participants

Reaction Steps

Prepared according to the procedure for Example 16, using (cis)-tert-butyl 3-fluoro-4-(methylsulfonyloxy)piperidine-1-carboxylate in place of tert-butyl 2-((methylsulfonyloxy)methyl)morpholine-4-carboxylate and 2-(7-ethylimidazo[1,2-a]pyridin-3-yl)quinolin-8-ol in place of 2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-ol. MS APCI (+) m/z 391.2 (M+1) detected.

Provenance & Evidence