Acetaldehyde → HCID 66781425, compound

HRID 1095743Notes

Reaction equation

[F:1][C@H:2]1[C@H:7]([O:8][C:9]2[CH:10]=[CH:11][CH:12]=[C:13]3[C:18]=2[N:17]=[C:16]([C:19]2[N:23]4[CH:24]=[CH:25][C:26]([O:28][CH2:29][CH2:30][O:31][CH3:32])=[CH:27][C:22]4=[N:21][CH:20]=2)[CH:15]=[CH:14]3)[CH2:6][CH2:5][NH:4][CH2:3]1.[CH:33](=O)[CH3:34]>>[CH2:33]([N:4]1[CH2:5][CH2:6][C@@H:7]([O:8][C:9]2[CH:10]=[CH:11][CH:12]=[C:13]3[C:18]=2[N:17]=[C:16]([C:19]2[N:23]4[CH:24]=[CH:25][C:26]([O:28][CH2:29][CH2:30][O:31][CH3:32])=[CH:27][C:22]4=[N:21][CH:20]=2)[CH:15]=[CH:14]3)[C@H:2]([F:1])[CH2:3]1)[CH3:34]

Participants

Reactant 2

HCID 177Acetaldehyde

HCID 59176329HCID 59176329, compound

Product 1

HCID 66781425HCID 66781425, compound

Procedure

Prepared from 8-((trans)-3-fluoropiperidin-4-yloxy)-2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinoline according to the procedure for Example 29, using acetaldehyde in place of formaldehyde. MS APCI (+) m/z 465.1 (M+1) detected.

Sources & evidence

ORD record: ord-d05580b3aecf4981840fcfbdbde632c3
Source dataset: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08138181B2

Reaction notes

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