HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095763Generated: November 1, 2026
Methyl 3-(cyclopentyloxy)-4-methoxy-2-nitrobenzoate → Methyl 2-amino-3-(cyclopentyloxy)-4-methoxybenzoate
https://huagongshe.com/reaction/1095763
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl 3-(cyclopentyloxy)-4-methoxy-2-nitrobenzoate | HCID 66781723 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-amino-3-(cyclopentyloxy)-4-methoxybenzoate | HCID 66781747 | — |
Reaction Steps
A mixture of methyl 3-(cyclopentyloxy)-4-methoxy-2-nitrobenzoate (750 mg, 2.54 mmol), 10% Pd/C (50% H2O, 500 mg, 0.23 mmol Pd), and methanol (10 mL) was stirred vigorously at 23° C. under an atmosphere of H2. After 21 h, the mixture was filtered through Celite and concentrated to give methyl 2-amino-3-(cyclopentyloxy)-4-methoxybenzoate: MS (ESI): 266.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08138205B2 |
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| Source dataset | uspto-grants-2012_03 |
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| ORD ID | ord-20d385e861a541a3b3b383c84a0a6184 |
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| Source note | uspto-grants-2012_03 |
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