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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095779Generated: October 30, 2026

1,4-Dibromobutane → 8-(4-Bromobutoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxyquinolin-2(1H)-one

https://huagongshe.com/reaction/1095779

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DibromobutaneHCID 8056—
Reactant4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxyquinolin-2(1H)-oneHCID 59268118—
Product8-(4-Bromobutoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxyquinolin-2(1H)-oneHCID 66781738—

Reaction Steps

8-(4-Bromobutoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxyquinolin-2(1H)-one was prepared from 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxyquinolin-2(1H)-one (Example 11, Step 1) and 1,4-dibromobutane following the procedure outlined in Example 11, Step 2. MS (ESI): 485.8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138205B2
Source datasetuspto-grants-2012_03
ORD IDord-9e4c5c0c16ca4e189c38b8478945bf50
Source noteuspto-grants-2012_03