HCID 23151271, compound → HCID 66783670, compound

HRID 1095834Notes

Reaction equation

HRID 1095834 reaction equation
CC1C=CC(S(O)(=O)=O)=CC=1.[CH3:12][C@@H:13]1[CH2:17][CH2:16][CH2:15][N:14]1[CH2:18][CH2:19][CH2:20][O:21][C:22]1[CH:28]=[CH:27][C:25]([NH2:26])=[CH:24][CH:23]=1.C1(N2[CH2:38][CH2:37][CH:36]([O:39]C3C=CC(N)=CC=3)[CH2:35][CH2:34]2)CCC1>>[CH3:12][C@@H:13]1[CH2:17][CH2:16][CH2:15][N:14]1[CH2:18][CH2:19][CH2:20][O:21][C:22]1[CH:23]=[CH:24][C:25]([N:26]2[CH2:38][CH2:37][C:36](=[O:39])[CH2:35][CH2:34]2)=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 23151271HCID 23151271, compoundHCID 86600242HCID 86600242, compound

Product 1

HCID 66783670HCID 66783670, compound

Procedure

The entitled compound was obtained as a brown oily substance, according to the same method as in Reference Example 21 or according to a method similar to it but using 4-{3-[(2R)-2-methylpyrrolidin-1-yl]propoxy}aniline 4-methylbenzenesulfonate produced according to a method described in a patent (WO2005/077905), as the starting compound in place of 4-[(1-cyclobutylpiperidin-4-yl)oxy]aniline.

Workup

  1. customThe entitled compound was obtained as a brown oily substance
  2. customproduced

Sources & evidence

ORD record
ord-dc902482a1394241984040ad20fdb551
Source dataset
uspto-grants-2012_03
Patent number
US08138206B2

Reaction notes

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