HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → [4-(3-Benzenesulfonylamino-benzene-sulfonyl-amino)-4,5,6,7-tetrahydro-indazol-1-yl]-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | [4-(3-Amino-benzenesulfonylamino)-4,5,6,7-tetrahydro-indazol-1-yl]-acetic acid ethyl ester | HCID 59152902 | — |
| Product | [4-(3-Benzenesulfonylamino-benzene-sulfonyl-amino)-4,5,6,7-tetrahydro-indazol-1-yl]-acetic acid ethyl ester | HCID 59153039 | 70% |
Reaction Steps
Stating with [4-(3-amino-benzenesulfonylamino)-4,5,6,7-tetrahydro-indazol-1-yl]-acetic acid ethyl ester and benzenesulfonyl chloride, and using the method analogous to the one described for example 14-1, [4-(3-benzenesulfonylamino-benzene-sulfonyl-amino)-4,5,6,7-tetrahydro-indazol-1-yl]-acetic acid ethyl ester (15 mg, 70%) was obtained as a white solid. MS cald. for C23H26N4O6S2 518, obsd. (ESI+) [(M+H)+]:519.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08138208B2 |
| Source dataset | uspto-grants-2012_03 |
| ORD ID | ord-4480936aa52c4e68ae2a7e0610279d98 |
| Source note | uspto-grants-2012_03 |