Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 6-chloropyridazine-3-carboxylate → 6-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenoxy}-pyridazine-3-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 6-chloropyridazine-3-carboxylate | HCID 12379801 | — |
| 반응물 | 3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenol | HCID 25254146 | — |
| 생성물 | 6-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenoxy}-pyridazine-3-carboxylic acid methyl ester | HCID 59508643 | — |
반응 단계
The title compound was prepared in analogy to Example 93, step 7 from 3-chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenol (obtained in Example 93, step 6) by alkylation with methyl-6-chloropyridazine-3-carboxylate [CAS Reg. No. 65202-50-8]. MS (m/e)=482.0 [MH+].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08138189B2 |
| 출처 데이터셋 | uspto-grants-2012_03 |
| ORD ID | ord-581ba622f2674a0f989f0595c4fc0895 |
| 출처 메모 | uspto-grants-2012_03 |