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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1095938Generated: November 1, 2026

Methyl 5-chloropyrazine-2-carboxylate → HCID 59508652, compound

https://huagongshe.com/reaction/1095938

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 5-chloropyrazine-2-carboxylateHCID 406081—
Reactant3-Chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenolHCID 57421264—
ProductHCID 59508652HCID 59508652—

Reaction Steps

The title compound was prepared in analogy to Example 93, step 7 from 3-chloro-4-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenol (obtained in Example 19, step 5) by alkylation with methyl-5-chloropyrazine-2-carboxylate [CAS Reg. No. 33332-25-1]. MS (m/e)=502.0 [MH+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08138189B2
Source datasetuspto-grants-2012_03
ORD IDord-8eef29b457f14882a92e83e717c155ed
Source noteuspto-grants-2012_03