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HRID1095946

反应详情

EQUATION

反应方程式

HRID 1095946 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc(Cl)nc1
HCID254249

2-Chloro-5-(methoxycarbonyl)pyridine

C7H6ClNO2

结构：CC(c1ccc(CO)cc1Cl)C(O)(c1ccnc(Cl)c1)C(F)(F)F
HCID25254449

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(OCc2ccc(C(C)C(O)(c3ccnc(Cl)c3)C(F)(F)F)c(Cl)c2)nc1
HCID72310577

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to Example 93, step 7 from 3-(2-chloro-4-hydroxymethyl-phenyl)-2-(2-chloro-pyridin-4-yl)-1,1,1-trifluoro-butan-2-ol (obtained in Example 120, step 1) by alkylation with methyl-6-chloronicotinate [CAS Reg. No. 73781-91-6]. MS (m/e)=515.1 [MH+].