(4-Chloro-3-(ethoxycarbonyl)phenyl)boronic acid → HCID 66782596, compound

Participants

Reaction Steps

In analogy to Example 150, step 2, 5-[2-(4-bromo-2-chloro-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1-methyl-1H-pyridin-2-one (Example 165, step 3) was reacted with 4-chloro-3-ethoxycarbonylphenylboronic acid. The product of this reaction was hydrolyzed in analogy to Example 141 to give the title compound as a colorless solid. MS (m/e, ISP neg. ion)=498.1 [M−H+].

Provenance & Evidence