N(1)-methyl-2-pyridone-5-carboxylic acid → HCID 66699447, compound

HRID 1096012Notes

Reaction equation

HRID 1096012 reaction equation
CO[C:3](=O)[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([Cl:13])[C:6]=1[Cl:14].[CH3:16][N:17]1[C:22](=[O:23])[CH:21]=[CH:20][C:19]([C:24]([OH:26])=O)=[CH:18]1>>[Cl:14][C:6]1[C:7]([Cl:13])=[C:8]([O:11][CH3:12])[CH:9]=[CH:10][C:5]=1[CH:4]([CH3:3])[C:24]([C:19]1[CH:20]=[CH:21][C:22](=[O:23])[N:17]([CH3:16])[CH:18]=1)=[O:26]

Participants

3

Reactant 2

HCID 592704N(1)-methyl-2-pyridone-5-carboxylic acidHCID 57421333HCID 57421333, compound

Product 1

HCID 66699447HCID 66699447, compound

Procedure

The title compound was prepared in analogy to Example 189, steps 1-3, from (2,3-dichloro-4-methoxyphenyl)acetic acid methyl ester and 1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid. Colorless solid. MS (m/e)=340.1 [M+H+].

Sources & evidence

ORD record
ord-8fcb1bc3c4214905aa5a07657144387a
Source dataset
uspto-grants-2012_03
Patent number
US08138189B2

Reaction notes

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