Sodium Chlorite → HCID 72310561, compound

Participants

Reaction Steps

In analogy to Example 214, step 2, 4-{3-chloro-4-[2-(1,5-dimethyl-6-oxo-1,6-dihydro-pyridin-3-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenoxy}-3-trifluoromethyl-benzaldehyde was treated with sodium chlorite in the presence of sodiumdihydrogenphosphate-dihydrate in tert.-butanol, 2-methyl-2-butene and water to give the title compound as a colorless solid. MS (m/e, ISP neg. ion)=562.0 [M−H+].

Provenance & Evidence